Objective: To explore the decision-making of therapeutic drug application and the dose adjustment of vancomycin based on blood concentration monitoring in a child with infective endocarditis and osteomyelitis

so as to analyze the role of clinical pharmacists in anti-infective treatment. Methods: Omnidirectional pharmaceutical care and pharmaceutical consultation were performed on a child with infective endocarditis and osteomyelitis. Individualized drug administration regimen was adjusted according to the results of vancomycin blood concentration. Results: During the treatment

situations such as the drug-related hypersensitivity reaction

recrudescent symptoms and abnormal blood concentration were observed. With the participation of clinical pharmacists for many consultations and the whole process of monitoring

the child was discharged from the hospital after improved anti-infective treatment. Conclusion: Clinical pharmacists have professional advantages in anti-infective treatment optimization

adverse drug reaction assessment and management

blood concentration monitoring and individualized drug administration adjustment

and play an important role in the treatment of severe infection in children

fully reflecting the professional value of clinical pharmacists.